It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Isosorbide Manufacturing: An In-Depth Look at Production Costs and That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. If you notice other effects not listed above, contact your doctor or pharmacist. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. In: Textbook of Natural Medicine. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. If you have an eye condition called glaucoma. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Natural Medicines. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). Accessed Sept. 7, 2022. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. This document does not contain all possible drug interactions. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. The tablet usually is taken two or three times daily. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Careers. See also: nitroglycerin side effects in more detail. HHS Vulnerability Disclosure, Help If we combine this information with your protected Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Aspirin relieves pain and inflammation and helps to thin the blood. Take the missed dose as soon as you remember it. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. 5.0 out of 10 from a total of Along with its needed effects, a medicine may cause some unwanted effects. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Epub 2006 Mar 22. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Avoid combinations; the risk of the interaction outweighs the benefit. It works to relax your blood vessels. Hawthorn. You may report side effects to Health Canada at 1-866-234-2345. Results: Does Alcohol Raise Your Blood Pressure? Higher dosages are associated with stomach irritation and Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Do not take a double dose to make up for a missed one. If it is within 2 hours of the next dose, skip the missed dose. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. Using this medicine with any of the following medicines is not recommended. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. This drug may make you dizzy. Use this medication regularly to get the most benefit from it. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. If this worries you, talk to your doctor or pharmacist about other options. https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate belongs to the group of medicines called nitrates. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Many common herbal supplements interact with common heart medicines. Keep all medications away from children and pets. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. The most common side-effect is headache. We study millions of patients and 5,000 more each day. All rights reserved. Compare a few possible alternatives below. Isosorbide Mononitrate - Medicine.com It has a very short duration of action and may not be suitable for some people. Isosorbide Mononitrate - Uses, Side Effects, and More - WebMD Accessed Sept. 7, 2022. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Mehta D. Herbal & dietary supplements. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Botanical medicine A modern perspective. It works and leaves the body quickly, so it needs to be taken twice a day. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). To help you remember, take it at the same times each day. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Now, youll enjoy a streamlined experience created specifically for healthcare providers. 2023 eHealthMe.com. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. All Rights Reserved. Cardizem Alternatives Compared - Drugs.com Take this medication by mouth as directed by your doctor, usually twice a day. It might help to take isosorbide mononitrate and dinitrate after meals. Of the total drug interactions, Do not take more or less of it or take it more often than prescribed by your doctor. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Some side effects may occur that usually do not need medical attention. My cardiologist recommended I get on metropolol. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Isosorbide mononitrate - Wikipedia Other medications may be prescribed by your doctor for these conditions. Consult your doctor for more details. Methods: Egton Medical Information Systems Limited. include protected health information. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. from the best health experts in the business. Normal ecg doesn't rule out heart disease. Available for Android and iOS devices. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Keep all medicines out of the reach and sight of children. 1998 Oct;61(10):577-83. Take isosorbide exactly as directed. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Bethesda, MD 20894, Web Policies And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. This content does not have an English version. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. government site. Natural Medicines. Minimally clinically significant. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Isosorbide tablets are also used with other medications to treat heart failure. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty All rights reserved. Registered in England and Wales. This medication belongs to a class of drugs known as nitrates. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Some of these medicine interactions can be risky. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. Generic alternatives may be available. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Imdur vs. Isordil - RxList Bauer B (expert opinion). The extended-release tablet usually is taken once daily in the morning. This product is available in the following dosage forms: There is a problem with However, you should not flush this medication down the toilet. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. It is unknown if this medication passes into breast milk. Never give it to other people even if their condition appears to be the same as yours. Keep this medication in the container it came in, tightly closed, and out of reach of children. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. This does not necessarily mean no interactions exist. isosorbide mononitrate, along with This risk may be even higher for certain groups. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. You can consult me online for homeopathic treatment. Although not all of these side effects may occur, if they do occur they may need medical attention. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. We don't support your browser. Advertising revenue supports our not-for-profit mission. Isosorbide mononitrate (Monoket) can cause some serious health issues. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. https://naturalmedicines.therapeuticresearch.com. It can make you really dizzy. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Things to remember when you fill your prescription. information highlighted below and resubmit the form. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. This makes it easier for your heart to pump, relieving heart-related chest pain. Canada residents can call a provincial poison control center. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. This is a condition where the heart does not beat as efficiently as it should. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. If you have any questions about this medicine ask your pharmacist. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Drug information provided by: IBM Micromedex. https://naturalmedicines.therapeuticresearch.com. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). [2] It is taken by mouth. Available for Android and iOS devices. Do not change the dosing times unless directed by your doctor. Please see a good cardiologist, get admitted, get checked thoroughly. https://www.uptodate.com/contents/search. Unless there is a specific reason you need the brand, the generic medication will be a better value. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. It is important that you follow the instructions your doctor gives to you about when to take your doses. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Store in a cool, dry place, away from direct heat and light. the unsubscribe link in the e-mail. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. This medicine is available only with your doctor's prescription. The IR version can help treat and prevent angina. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. . Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Mehta D. Botanical medicines. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Natural Medicines. Talk to your pharmacist for more details. Can isosorbide mononitrate cause problems? Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma
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